Si avvisa che

in data 31-05-2024, alle ore 14:30 precise

al Politecnico di Milano, in aula B.51 (edificio 14),

si svolgerà il seguente seminario

Prof. Richard Samworth, Cambridge

Titolo: Isotonic subgroup selection and its role in clinical trials

Abstract: Given a sample of covariate-response pairs, we consider the subgroup selection problem of identifying a subset of the covariate domain where the regression function exceeds a pre-determined threshold. This is particularly relevant in clinical trials and other applications in the life sciences, for instance where we might want to determine a subgroup that would benefit from a vaccine or treatment. We introduce a computationally-feasible approach for subgroup selection in the context of multivariate isotonic regression based on martingale tests and multiple testing procedures for logically-structured hypotheses. Our proposed procedure satisfies a non-asymptotic, uniform Type I error rate guarantee with power that attains the minimax optimal rate up to poly-logarithmic factors. Extensions cover classification, isotonic quantile regression and heterogeneous treatment effect settings.

Il link per seguire il seminario online sarà reso disponibile pochi minuti prima dell’avvio del seminario al seguente link https://mox.polimi.it/mox-colloquia-seminars-list/mox-seminars/?id_evento=24...

Questa iniziativa è parte delle Ph.D. Lectures finanziate dal Dipartimento di Eccellenza, 2023-2027, Dipartimento di Milano, Politecnico di Milano.

Cordialmente, Laura Sangalli

—— Laura Maria Sangalli MOX - Dipartimento di Matematica Politecnico di Milano Piazza Leonardo da Vinci 32 20133 Milano - Italy (+39) 02 2399 4554 laura.sangalli@polimi.itmailto:laura.sangalli@polimi.it https://sangalli.faculty.polimi.it